Novel Lipids Pharmacognosy Solutions

Novel Lipids Pharmacognosy Solutions

Optimizing Patient Outcomes For Those Suffering From An Impaired ∆-6 Desaturase Metabolic Pathway

EZTREK® is not a medicine and is not intended to treat, diagnose, mitigate, prevent, or cure diseases.

Peskin Pharmaceuticals® was founded to research, develop, and ultimately commercialize therapeutics for disorders of the ∆-6metabolic pathway leading to increased inflammation. Today, many people’s diets unknowingly may cause chronic inflammation leading to ill-health.1,2 As we age, this pathway is known to become impaired.3 Eicosanoid optimization starts with the ∆-6 metabolic pathway:

  1. Halbleib, K., et al., “Activation of the Unfolded Protein Response by Lipid Bilayer Stress,” Molecular Cell, Vol. 67, Issue 4, pp 673-684.e8, August 17, 2017; “Molecular biologists discover an active role of membrane lipids in health and disease,” August 4, 2017 in biology / cell & microbiology,
  2. Anton SD, et al., “Differential effects of adulterated versus unadulterated forms of linoleic acid on cardiovascular health,” J’ Integr Med, 2013; 11(1): 2–10.
  3. Horrobin, DF, “Loss of -6 desaturase activity as a key factor in aging,” Medical Hypothesis. (1981) sep;7(9): 1211-20.
  1. 4. E. Wainwright, Y. S. Huang, et al., “The Effects of Dietary n-3 / n-6 Ratio on Brain Development in the Mouse: A Dose Response Study with Long-Chain n-3 Fatty Acids,” Lipids, vol. 27, no. 2, pp. 98-103, 1992.
  2. 5. W. E. M. Lands, et al., “Quantitative effects of dietary polyunsaturated fats on the composition of fatty acids in rat tissues,” Lipids, vol. 25, no. 9, pp. 505-516, 1990.
  3. 6. C. V. Felton, et al., “Relation of Plaque Lipid Composition and Morphology to the Stability of Human Aortic Plaques,” Arteriosclerosis, Thrombosis, and Vascular Biology,” Vol. 17, No 7, 1997, pp. 1337-1345.

Applying unique insights into the epigenetic pathways, our approach focuses on state-of-the-art research — based on recognized scientific principles, and supported extensively in the scientific literature (See below.). The culmination of over 2 decades of research led to developing a plant-based lipids composition (Medical Food) to help improve inflammation-related problems.

Our methodology is unique. We focus on supporting and optimizing the patient’s natural physiologic processes; not blocking or impeding metabolic pathways. The results are novel and often highly effective.

Peskin Pharmaceuticals® has developed a medical food, EZTREK® — specially for dietary management with distinctive nutritional requirements, helping to compensate for an impaired delta-6 desaturase metabolic pathway, as diagnosed and evaluated by your physician. This patented, botanical-based lipids formulation is not duplicated by normal / typical dietary modification alone.

Medical Food EZTREK®